mRNA Vaccines - Development & Manufacturing

This training course provides participants with a deeper understanding of the processes and challenges in the field of mRNA vaccine development and manufacturing. The course has a large hands-on component.

Duration
2 days
Course fee
€ 1985 (excl. VAT)

Short description

This two-day course covers the fundamentals of the most essential topics in mRNA vaccine development and manufacturing. Designed for professionals in the biopharmaceutical industry, this course covers the entire mRNA production process, from the basics of mRNA technology to the complexities of manufacturing and quality control. This training program mimics real-life scenarios as much as possible by using state of the art equipment, knowledge from industry experts, and our cleanroom training area's.

Objectives

  • Learn about fundamentals of mRNA technology
  • Understanding the mRNA manufacturing process flow
  • Learn about raw materials, Plasmid design & production, Fermentation techniques, mRNA purification and Filtration principles (TFF)
  • Learn about In Vitro Transcription
  • Gain practical experience with the Encapsulation process in lipid nanoparticles with state of the art technology
  • Performing and understanding the most essential QC tests in mRNA.
  • Basics of QA/RA and Technology Transfer in relation to mRNA vaccines.

Target group

  • Anyone involved in or interested in mRNA vaccine technology and its manufacturing processes
  • Biopharmaceutical professionals
  • Scientists
  • Engineers
  • CMO's, CDMO's

Program

Day 1

09:00

1. Welcome & Introduction
2. Pre-assessment quiz
3. Introduction to GMP manufacturing process of mRNA vaccines
Theory and workshop
4. Plasmid design
Theory and workshop
5. Plasmid production, cell harvest and lysis
Practice & demo
6. Plasmid linearization and in vitro transcription (IVT)
Practice & Workshop


Day 2

09:00

1. Ultrafiltration and diafiltration
Theory and practice
2. Delivery systems for mRNA vaccines
Theory and workshop
3. QC testing for mRNA and LNP formulation
Theory and Practice
4. Internal Technology Transfer (from lab to GMP)
Theory and workshop



Sign up

Interested in signing up a group of people for this course?

Please contact our Business Development team:
info@biotechtrainingfacility.nl
+31 (0)88 2830100

Need help? Have a question or a suggestion maybe?

Drop us a line below or call us on
+31 (0) 88 283 01 00.

Thanks